Talk by Alex Ireland: Human Models of Bone Mechanoadaptation

UPDATE: See update post here

On Thursday 26th October we will be hosting Dr Alex Ireland, Lecturer from the School of Healthcare Science at the Manchester Metropolitan University to give a talk on Human models of bone mechanoadaption.  The talk will take place at 13:00 in G39, Polly Vacher building, University of Reading.

The abstract for the talk can be found bellow:

“Fractures caused by osteoporosis (low bone strength) are a common, expensive health problem, affecting >3m EU citizens annually costing ~€30bn. Bone adapts to the large muscle and reaction forces it experiences during movement, such that mechanical loading is a primary determinant of bone size and strength. For example, athletes have up to 40% greater bone mass than sedentary individuals whereas reduced loading following spinal cord injury leads to loss of up to 50% bone mass. This influence is evident throughout life, from effects of fetal movements and the onset of independent walking on skeletal development, to exercise benefits to bone observed even in the tenth decade of life. However, the evident potential of loading to improve and maintain bone strength suggested by observational studies remains largely unfulfilled in interventional trials. Recent methodological advances have led to greater understanding of the mechanical environment of bone and the physiology underlying bone mechanoadaptation, which will improve our ability to design effective interventions.

I will present recent findings obtained from study of models of human loading across the lifespan by our group and other colleagues in the field. In addition, I will propose how employment of this knowledge can improve and maintain bone health and reduce fracture risk in individuals of all ages”

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